摘要
目的观察分析结肠癌患者采用完整结肠系膜切除手术治疗的临床效果。方法将74例结肠癌手术治疗患者随机分为观察组(采用完整结肠系膜切除术治疗)和对照组(采用传统结肠癌手术治疗)各37例,对比观察两组患者术中出血量、淋巴结清除数、临床并发症发生率、复发率以及3年和4年生存率。结果观察组术中出血量少于对照组,淋巴结清除数高于对照组,差异有统计学意义(P﹤0.05)。观察组吻合口瘘(2.7%)、残端肿瘤残余率(2.7%)及复发率(8.1%)均低于对照组(18.9%、16.2%、27.0%),两组比较差异有统计学意义(P﹤0.05)。观察组3年生存率(91.9%)、4年生存率(67.6%)高于对照组的67.6%、40.5%,两组比较差异有统计学意义(P﹤0.05)。结论结肠癌患者采用完整结肠系膜切除治疗的临床效果良好,可最大限度切除淋巴组织以及系膜,降低术后并发症发生率以及局部复发率,改善患者的生存质量,提高术后生存时间。
Objective To observe the clinical effect of complete mesocolic excision （CME） in the treatment of patients with colon cancer patients. Method 74 cases of colon cancer were included in this study, and were randomized into either study group （with CME treatment） or control group （with conventional surgery for colon cancer）, with 37 cases in each. The intraoperative bleeding volume, number of dissected lymph nodes, clinical complications, recurrence rate, as well as the 3- and 4-year survival rate of the two groups were compared. Result The study group had a significantly lower intraoperative bleeding volume, and more dissected lymph nodes compared with the control group （P〈0.05）, and the incidences of anastomosis fistula （2.7%）, residual tumor at the resected stump （2.7%） as well as the recurrence rate （8.1%） were all significantly lower in the study group than those of the control group （18,9%, 16.2% and 27.0%） （P〈0.05）. The 3- year （91.9%） and 4-year survival rate （67.6%） in the study group were also significantly higher than that in the control group at 67.6%, 40.5%, respectively （P〈0.05）. Conclusion Complete mesocolic excision is effective in the treatment of colon cancer, which guarantees the maximal resection of lymphoid tissue and mesentery, reducing postoperative complications and local recurrence rate, improving the quality of life and survival for patients.
出处
《癌症进展》
2016年第3期248-250,共3页
Oncology Progress
