消咳喘胶囊联合氨茶碱治疗小儿咳嗽变异性哮喘的临床观察

Clinical observation of Xiaokechuan capsules combined with Aminophylline in treatment of cough variant asthma of children

目的:观察消咳喘胶囊联合氨茶碱对小儿咳嗽变异性哮喘的临床疗效。方法:将90例咳嗽变异性哮喘患儿随机分为对照组和治疗组,每组各45例。对照组患儿给予口服氨茶碱治疗;治疗组患儿给予口服消咳喘胶囊联合氨茶碱治疗两组患者治疗周期均为2周。比较两组患儿的治疗效果,并对临床症状进行评分。结果:治疗2周后,对照组患儿的显效率为82.22%,其中治愈29例,显效8例,无效8例;治疗组患儿的显效率为93.33%,明显高于对照组(P<0.05),其中治愈33例,显效9例,无效3例,治疗组患儿的临床症状的改善情况的评分优于对照组,差异明显(P<0.05)。结论:消咳喘胶囊联合氨茶碱治疗小儿咳嗽变异性哮喘患儿的临床疗效优于单纯氨茶碱治疗。

Objective:To investigate clinical efficacy of Xiaokechuan capsules and Aminophylline in treatment of cough variant asthma of children. Methods:90 children with cough variant asthma were divided into control group and treatment group with 45 cases in each group. The control group orally took Aminophylline, while the treatment group orally took Xiaokechuan capsules and Amin-ophylline. The treatments lasted two weeks. The efficacies and clinical symptoms of the two groups were observed and compared. Re-sults:After the treatment, the total efficiency of control group was 82. 22%, wherein 29 patients were cured, 8 patients were effective, and 8 patients were invalid, while the total efficiency of treatment group was 93. 33%, which was significantly higher than that of con-trol group (P<0. 05), wherein 33 patients were cured, 9 patients were effective, and 3 patients were invalid. The improvement of the clinical symptoms of treatment group was better than that of control group, and the difference was significant (P<0. 05). Conclusions:In the treatment of cough variant asthma of children, Xiaokechuan capsule combined with aminophylline shows better curative effects than single Aminophylline.