慢性胃炎脾胃虚实证型间口腔与胃黏膜Hp感染的对比研究

A comparative study on Hp infection of oral cavity and gastric mucosa between spleen-stomach deficiency syndrome and spleen-stomach excess syndrome in patients with chronic gastritis

目的:通过对慢性胃炎脾胃湿热证、脾气虚证患者的牙垢及胃黏膜Hp定性检测,分析不同中医证型在口腔及胃内Hp感染的差异性。方法:搜集脾胃湿热证和脾气虚证的慢性胃炎患者共84例,两组各42例,对所有患者进行14C尿素呼气试验和牙垢Hp定性检测。结果:脾胃湿热证组和脾气虚证组的口腔Hp感染率分别为76.2%和69.0%,差异无统计学意义(P>0.05);脾胃湿热证组和脾气虚证组的胃黏膜Hp感染率分别为73.8%和52.4%,差异有统计学意义(P<0.05)。结论:慢性胃炎脾胃湿热证与胃黏膜Hp感染密切相关。

Objective Based on the qualitative determination of tartar and gastric mucosal Hp in patients with chronic gastritisof spleen and stomach deficiency and excess syndrome, the difference of Hp infection of oral cavity and gastric mucosa in patients withdifferent TCM syndromes was analyzed. Methods： 84 patients with chronic gastritis of spleen and stomach damp heat syndrome and spleenQi deficiency syndrome were collected, 42 cases in each group. All the patients underwent 14C urea breath test and Hp test of tartar. Results：The infection rates of Hp in the spleen and stomach damp heat syndrome group and spleen Qi deficiency syndrome group were 76.2% and69.0% respectively; the difference was not statistically significant （P〉0.05）. The Hp infection rate of gastric mucosa in spleen and stomachdamp heat syndrome group and spleen Qi deficiency syndrome group were 73.8% and 52.4% respectively; the difference was statisticallysignificant （P〈0.05）. Conclusion： Chronic gastritis of spleen and stomach damp heat syndrome is closely related to the Hp infection ofgastric mucosa.