204例心脏永久起搏器植入术患者围术期抗菌药物预防性应用分析

Analysis on Prophylactic Use of Antibiotics in 204 Cases with Heart Permanent Pacemaker Implantation Surgery During Perioperation

目的:了解心脏专科医院心脏永久起搏器植入术预防性应用抗菌药物的基本情况,以期为医院规范围术期预防性应用抗菌药物和建立有效的干预措施提供参考。方法:调查武汉亚洲心脏病医院(以下简称"我院")2014年1—6月心脏永久起搏器植入术患者221例,统计并分析其预防性应用抗菌药物的情况。结果:221例患者中,符合入选标准的仅204例。纳入的204例患者中,抗菌药物预防性使用率为100%;预防性给药时间合理的有179例(占87.75%);预防性给药持续时间合理的有175例(占85.78%)。预防性使用的抗菌药物涉及4大类,使用病例数最多的为头孢菌素类(182例),其余为β-内酰胺酶抑制剂复方制剂(1例)、氟喹诺酮类(1例)、林可酰胺类(20例)。结论:我院心脏永久起搏器植入术围术期预防性应用抗菌药物存在不合理现象,应引起临床医师重视。

OBJECTIVE：To investigate the basic situation of prophylactic use of antibiotics in heart permanent pacemaker implantation surgery during perioperation in a heart specialized subject hospital,so as to provide reference for the standardize use of antibiotics and establish effective intervention measures.METHODS：221 patients with heart permanent pacemaker implantation surgery admitted into Wuhan Asia Heart Hospital（hereinafter referred to as ＂our hospital＂） from Jan.to Jun.2014 were investigated,statistical analysis was conducted on the prophylactic use of antibiotics.RESULTS：Of the 221 cases,there were only 204 cases met the criteria.As for the 204 cases,the prophylactic use rate of antibiotics was 100%;179 cases（87.75%） were in rational administration time.Duration of prophylactic administration were 175 cases（85.78%）.There were 4 kinds of prophylactic use of antibiotics,cephalosporin（182 cases） took the lead of number of cases,followed by β-lactamase inhibitor compound（1 case）,fluoroquinolone（1 case） and lincosamide（20 cases）.CONCLUSIONS：The prophylactic use of antibiotics in heart permanent pacemaker implantation surgery during perioperation was irrational to some extent,it is necessary to attach more importance by the clinicians.