高频振动通气在早产儿合并重症肺病中的应用效果及护理干预

Effect of high frequency oscillation ventilation and nursing intervention in treatment of preterm infants with severe lung diseases

目的探究高频振动通气在早产儿合并重症肺病中的应用效果及护理干预。方法选取合并重症肺病的早产儿120例随机分为2组,观察组60例患儿选用高频震荡通气进行治疗,对照组60例患儿选择常频机械通气进行治疗,比较2组患儿治疗过程中的动脉血氧分压[p(O_2)]、动脉血二氧化碳分压[p(CO_2)]、氧合指数(OI)、并发症发生率和转归。结果观察组患儿的总有效率为95.00%,显著高于对照组的总有效率80.00%(P<0.05);治疗后8 h、24 h、48 h,2组p(O_2)均随着时间的推移逐渐提高,而2组的p(CO_2)、OI则随着时间的推移逐渐降低,观察组的p(O_2)、p(CO_2)、OI在治疗后8 h、24 h、48 h较之前不断显著改善,且均显著优于同时间段的对照组,差异有统计学意义(P<0.05);观察组的并发症发生率显著低于对照组(P<0.05);观察组患儿的总治愈率为98.33%,显著高于对照组的总治愈率68.33%(P<0.05)。结论高频振荡通气能有效改善患儿的肺换气、肺通气,可提高患儿治愈率,降低病死率,减少并发症的发生,值得临床推广。

Objective To explore the effect of high frequency oscillation ventilation and nursing intervention in treatment of preterm infants with severe lung diseases. Methods A total of120 preterm infants with severe lung diseases were randomly divided into two groups,60 cases in each group. The observation group was treated with high frequency oscillation ventilation,while control group was treated with normal frequency mechanical ventilation. The oxygen partial pressure p（O_2）,CO_2 partial pressure p（ CO_2）,oxygen index（ OI）,the incidence rate of complications and outcome were compared between two groups. Results The total effective rate was 95. 00% in the observation group,which was significantly higher than 80. 00% in the control group（ P〈0. 05）. After treatment of 8,24,48 hours,p（O_2） level increased gradually with passage of time while p（ CO_2） level and OI decreased gradually with passage of time,and these indexes in the observation group were significantly better than those in the control group（ P〈0. 05）. Incidence rate of complications in the observation group was significantly lower than the control group（ P〈0. 05）. Total cure rate was 98. 33% in the observation group,which was significantly higher than 68. 33% in the control group（ P〈0. 05）.Conclusion High frequency oscillatory ventilation can effectively improve the lung ventilation and pulmonary ventilation of children,improve the cure rate and reduce incidence rate of complications.