血清降钙素原对感染所致急腹症诊治作用的研究

Role of procalcitonin in the diagnosis and treatment of acute abdomen caused by infectious diseases

目的:评价血清降钙素原(PCT)对感染所致急腹症诊断和治疗的临床作用。方法:选取感染性疾病所致急腹症患者142例(感染组)和非感染性疾病所致急腹症患者82例(非感染组),在使用抗生素前检测血清PCT含量。结果:感染组与非感染组血清PCT含量比较差异有统计学意义(P<0.05)。将感染组按病情分为轻、重度,比较非感染、轻度感染、重度感染3组患者,轻、重度感染组间存在正相关关系(r=0.743,P=0.013)。结论:PCT有助于鉴别感染性疾病和非感染性疾病所致急腹症,并且和病情的严重程度有一定的相关性。

Objective：To evaluate the clinical utility of serum procalcitonin in patients with acute abdomen caused by infectious diseases.Method：A total of 224 patients with acute abdomen from Jan 2014 to Jan 2015 were enrolled in this study.There were 142 patients in infection group,while 82 patients in the non infection group.All patients were determined the level of serum PCT before antibiotic therapy.Result：Serum PCT didn＇t increase in the non infection group,increase in the bacterial infectious group.There were significant differences between the two groups（P〈0.01）.All patients were divided into non infection,mild and severe infectious patients,according to the condition.There was a positive correlation relationship between severity of infection and concentration of PCT（r=0.743,P=0.013）.Conclusion：PCT could be used in clinical algorithms to diagnose positive infections of acute abdomen.Different PCT levels could be related to different severity of infection.