康复新液联合解痉液防治放射性食管炎的临床观察

Clinical observation of Kangfuxin liquid combined with spasmolysis liquid in prevention and treatment of radiation esophagitis

目的观察康复新液联合口服解痉液防治食管癌放射性食管炎的疗效。方法 68例中晚期食管癌患者,随机分为实验组(35例)和对照组(33例)。实验组在口服解痉液基础上加用康复新液(康复新液10 ml+解痉液20 ml)防治放射性食管炎,对照组口服解痉液(解痉液20 ml)防治放射性食管炎。对比两组临床疗效。结果实验组和对照组防治放射性食管炎的有效率分别为91.43%和69.70%,两组比较差异具有统计学意义(P<0.05)。结论康复新液联合解痉液,对放射性食管炎具有比较明显的预防治疗作用,能明显降低食管癌放疗中放射性食管炎的发生率以及严重程度,值得临床推广。

Objective To observe curative effect by Kangfuxin liquid combined with spasmolysis liquid in prevention and treatment of esophagus cancer radiation esophagitis. Methods A total of 68 patients with moderate and advanced esophagus cancer were randomly divided into experimental group（35 cases） and control group（33 cases）. The experimental group received oral administration of spasmolysis liquid and additional Kangfuxin liquid（Kangfuxin liquid 10 ml ＋ spasmolysis liquid 20 ml） in prevention and treatment of radiation esophagitis. The control group received oral administration of spasmolysis liquid（spasmolysis liquid 20 ml） in prevention and treatment of radiation esophagitis. Clinical effects of the two groups were compared. Results Effective rates of the experimental group and the control group were respectively 91.43% and 69.70% in prevention and treatment of radiation esophagitis, and the difference had statistical significance between the two groups（P〈0.05）. Conclusion Combination of Kangfuxin liquid and spasmolysis fluid provides precisely preventive and curative effect for radiation esophagitis. This method can remarkably reduce incidence and severity of radiation esophagitis in esophagus cancer, and it is worth clinical promotion.