降钙素原与C-反应蛋白联合检测在肺部感染患者诊断中的应用

Application of combined detection of procalcitonin and C-reactive protein in diagnosis of pulmonary infection patiens

目的探讨降钙素原(PCT)与C-反应蛋白(CRP)联合检测在肺部感染诊断中的应用,指导临床准确诊断肺部感染。方法 68例肺部感染的患者作为感染组与同期68例健康体检者作为健康对照组,检测两组研究对象血清PCT及CRP的含量。结果感染组的PCT及CRP水平均高于健康对照组,差异有统计学意义(P<0.05);感染组PCT及CRP的检测阳性率分别为94.1%及85.3%,健康对照组分别为2.9%及8.8%,两组比较差异均有统计学意义(P<0.05)。结论 PCT与CRP联合检测在肺部感染的诊断和鉴别诊断中具有重要意义。

Objective To investigate application of combined detection of procalcitonin（PCT） and C-reactive protein（CRP） in diagnosis of pulmonary infection patients, and to guide accurately clinical diagnosis of pulmonary infection. Methods There were 68 patients with pulmonary infection as infection group and 68 healthy people at the same period as healthy control group. Their serum PCT and CRP contents were detected. Results The infection group showed all higher PCT and CRP contents than the healthy control group, and the difference had statistical significance（P〈0.05）. The infection group had positive detection rates of PCT and CRP as 94.1% and 85.3%, and those were 2.9% and 8.8% in the healthy control group. Their differences all had statistical significance（P〈0.05）. Conclusion Combined detection of PCT and CRP shows important significance in diagnosis and differential diagnosis of pulmonary infection.