期刊文献+

右美托咪定在老年患者术后谵妄护理中的应用

下载PDF
导出
摘要 目的:探讨右美托咪定在老年患者术后谵妄(POD)护理中的应用效果。方法:选择本院收治的2012年1月-12月择期POD老年患者72例,随机分为右美托咪定组(D组)34例和常规护理组(N组)38例。D组给予以右美托咪定,并给予围术期护理;N组仅给予围术期护理,躁动明显者给予氟哌啶醇,比较两组患者心率、平均动脉压、呼吸、血氧饱和度、意外伤害及谵妄转归情况。结果:两组患者心率、平均动脉压、呼吸比较,差异具有统计学意义(P<0.05),两组血氧饱和度比较,差异无统计学意义(P>0.05);D组意外伤害及谵妄转归均好于N组(P<0.05)。结论:右美托咪定能够安全有效的用于老年患者POD的护理。
出处 《深圳中西医结合杂志》 2016年第6期177-179,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献3

  • 1Gregory L,Fricchione,Shamim H,et al.Postoperative Delirium [J] .Am J Psychiatay,2008,165(7):803-812.
  • 2李民,张利萍,吴新民.右美托咪啶在临床麻醉中应用的研究进展[J].中国临床药理学杂志,2007,23(6):466-470. 被引量:483
  • 3van Eijk MM,Roes KC,Honing ML,et al.Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients:a multicentre,double- blind,placebo-controlled randomised trial [J] .Lancet. 2010,376(9755):1829-1837.

二级参考文献39

  • 1[1]Khan ZP,Ferguson CN,Jones RM.Alpha-2 and imidazoline receptor agonists:their pharmacology and therapeutic role[J].Anesthesia,1999;54:146-165.
  • 2[2]Kamibayashi T,Maze M.Clinical uses of alpha 2-adrenergic agonists[J].Anesthesiology,2000;93:1345-1350.
  • 3[3]Calzada BC,De Artinano AA.[alpha]2-Adrenoreceptor subtypes[J].Pharmacol Res,2001;44:195-208.
  • 4[4]Hunter JC,Fontanna DJ,Hedley LR,et al.Assessment of the role of alpha 2-adrenoceptor subtypes in the antinociceptive,sedative and hypothermic action of dexmedetomidine in transgenic mice[J].Br J Pharmacol,1997;122:1339-1344.
  • 5[5]Nelson LE,Lu J,Guo TZ,et al.The α2-Adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects[J].Anesthesiology,2003;98:428-436.
  • 6[6]Coull JT,Jones M,Egan T,et al.Attentionla effects of noradranaline vary with arousal level:selective activation of thalamie pulvinar in humans[J].Neuro Image,2004;22:315-322.
  • 7[7]Eisenach JC.[Alpha]2 agonists and analgesia[J].Exp Opin Invest Drugs,1994;3:1005-1010.
  • 8[8]Ma D,Rajakumamswamy N,Maze M.Alpha2-Adrenoceptor agonists:shedding light on neuroprotection?[J].Br Med Bull,2005;71:77-92.
  • 9[9]Ebert TJ,Hall JE,Barney JA,et al.The effects of increasing plasma concentrations of dexmedetomidine in humans[J].Anesthesiology,2000;93:382-394.
  • 10[10]Ramsey MA,Luterman DL.Dexmedetomidine as a total intravenous anesthestic agent[J].Anesthesiology,2004;101:787-781.

共引文献482

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部