茄属植物甾体皂苷成分及其药理活性研究进展

Steroidal saponins and their pharmacological activities in Solanum plants

茄科茄属植物全世界约有2 000多种,多分布于热带及亚热带地区,少数分布于温带地区。该文对近10年来文献报道的茄属植物中甾体皂苷成分及其药理活性研究进行了综述,该类化合物主要具有抗肿瘤、抗菌、抗炎、抗病毒、抗氧化、降糖降血脂等多种活性。茄属植物中的甾体皂苷类化合物具有很大的开发潜力和应用价值,该文为其进一步研究提供参考。

The genus Solanum which is the largest genus in Solanaceae consists of more than 2 000 species,most of them are distributed in tropics and subtropics areas,and only a small amount in temperate regions throughout the world. Steroidal saponins could be found in many species of the Solanum,and they are an important group of natural products exhbiting a number of potent beneficent properties,such as anti-tumor,antibacterial,antifungal,anti-inflammatory,antiviral,antioxidant,hypoglycemic,and antihyperlipidemic effects. As supplement,this paper gives a review of different structural categories of steroidal saponins and their pharmacological effects from the solanum plants over the past decade,and it is intended to provide a point of reference for further research on steroidal saponins in Solanum plants.