药源性男性乳腺发育症

Drug-induced Male Mammary Development

药物引起男性乳腺发育症（gynecomastia．GYN）占所有GYN的10％～25％．临床常用药物度他雄胺、非那雄胺、螺内酯、利培酮、西咪替丁等均可诱发男性乳腺发育症。本文通过对诱发男性乳腺发育的药物及其诱发GYN的作用机制进行分析总结，并概括了药源性GYN的诊断和治疗，以期为临床提供参考。

Drug-induced male mammary development （gynecomastia, GYN） accounts for 10% - 25% of all GYN.Clinical commonly used drugs such as finasteride, spironolactone, risperidone, cimetidine, etc all can induce male mammary development. This article tried to understand male breast development mechanism of action of drugs and it induced GYN, and summarized the diagnosis and treatment of drug-induced GYN, expecting to provide reference for clinical.