阵发性心房颤动冷冻球囊消融术后复发的预测因素分析

Predictors of recurrence after cryoballoon-based ablation for patients with paroxysmal atrial fibrillation

目的探讨阵发性心房颤动（AF）冷冻球囊消融术（CBA）后复发的预测因素。方法107例接受CBA治疗的阵发性AF患者，随访CBA术后早期（3个月内）AF复发和晚期（3个月后）AF复发的情况并分析复发的预测因素。结果24例（22．4％）在术后早期复发AF。多因素分析显示高敏C反应蛋白（hs—CRP）和血尿酸（SUA）是术后早期复发的独立预测指标。随访（10．32±3．54）个月，19例（17．8％）在术后晚期复发AF，其中18例为早期复发患者。多因素分析显示sUA是晚期AF复发的独立预测指标（OR：1．058；95％CI1．010～1．109，P〈0．017）。结论SUA和早期AF复发可作为CBA术后晚期AF复发的独立预测因素。

Objective To determine the predictors of recurrence after cryoballoon-based ablation（CBA） for pa- tients with paroxysmal atrial fibrillation（AF）. Methods One hundred and seven patients with paroxysmal AF who underwent CBA were enrolled in this study. Multivariate analysis were carried out to assess the predictors on early（within 3 months） and late （more than 3 months）recurrence of AF after the CBA procedure. Results Twenty-four（22. 4 % ）patients had early recurrence of AF after CBA. H s-CRP and SUA could predict the early recurrence of AF by multivariate analysis. During a follow-up of（10.32± 3.54）months, 19 （17.8 %） patients experienced late recurrence of AF, 94. 7 % （18/19） patients were experienced early recurrence. Multivariate analysis showed that SUA was the independent predictors for the late recurrence of AF（OR： 1. 058;95 %CI 1. 010-1. 109 ,P〈0. 017）. Conclusions SUA and early recurrence of AF are independent predictors for the late recurrence after CBA. [Chinese Journal of Cardiac Pacing and Electrophysiology , 2016,30 （2） ： 107-110]