国产与进口心脏单腔起搏器临床应用比较

Comparison study of the clinical application of domestic and imported cardiac single chamber pacemaker

目的比较国产心脏单腔起搏器(Qinming 2312)与两种进口心脏单腔起搏器(Biotronik PhilosⅡS、St.Jude 5056)的临床应用效果。方法连续入组在本院植入心脏单腔起搏器的患者74例,根据起搏器型号分为三组:A组(26例),植入Qinming 2312型;B组(25例),植入Biotronik PhilosⅡS型;C组(23例),植入St.Jude 5056型。检测并记录术后即刻和术后3个月随访时的各项起搏参数变化,采用SF-36量表评价并比较各组患者手术前后的生活质量改善情况,比较各组患者的起搏器费用及医保报销情况。结果与B、C组相比,A组患者手术即刻和术后3个月的各项起搏参数无显著差异(P>0.05),患者的生活质量各项指标评分无显著差异(P>0.05),而A组的费用较低,医保报销比例较高。结论国产心脏单腔起搏器(Qinming 2312)的性能及临床疗效不亚于进口单腔起搏器,具有更高的性价比。

Objective To compare the clinical application effect of domestic （Qinming 2312） and imported （Biotronik Philos II S, St. Jude 5056） cardiac single chamber pacemaker. Methods Seventy-four patients with single chamber pacemaker implanted in our hospital were divided into three groups according to the pacemaker brand： group A, Qinming 2312; group B, Biotronik PhilosH S; group C, St. Jude 5056. The parameters were recorded immediately after the operation and three months later. The quality of life of patients in each group were evaluated by SF-36 scale. We also compared the cost of pacemaker and medicare reimbursement ratio between each group. Results Compared to B and C group, the pacing parameters（include the pacing threshold,impedance and wave amplitude） of group A had no significant difference （P〉0.05） ; there was no significant difference in the quality of life of patients（P〉0.05） ; the cost of group A was cheaper, and the medicare reimbursement ratio was relatively higher. Conclusion The performance and clinical efficacy of the domestic pacemaker are comparable with the imported pacemakers, and the domestic pacemaker has higher ratio of performance to price. [Chinese Journal of Cardiac Pacing and Electrophysiology, 2016,30 （2） ： 146 -148]