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不同血压类型者冠状动脉血流储备的变化 被引量:1

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摘要 目的观察隐蔽性高血压(MHT)、白大衣性高血压(WCHT)和持续性高血压(SHT)者冠状动脉血流储备(CFR)的变化及其影响因素。方法连续入选初诊未经治疗的MHT 92人(MHT组)、WCHT103人(WCHT组)和SHT患者128例(SHT组)为观察对象,另入选同期健康体检正常血压者80人为对照组(NT组)。采用经胸超声心动图检测CFR。比较各组间CFR的差异,并分析其可能的影响因素。结果 SHT和WCHT组的诊室血压高于MHT和NT组(均P<0.05)。MHT和SHT组的24h收缩压和舒张压、白天和夜间动态血压高于WCHT组和NT组(均P<0.05)。MHT组和SHT组的CFR低于NT组和WCHT组(MHT组:2.33±0.25比SHT组:2.30±0.37比WCHT组:2.86±0.38比NT组:2.92±0.42,均P<0.05)。Pearson相关分析显示,在所有受试者中,CFR与高敏C反应蛋白(hsCRP,r=-0.243)、诊室收缩压(r=-0.164)和舒张压(r=-0.193)、24h动态舒张压(r=-0.457)和收缩压(r=-0.386)、白天动态收缩压(r=-0.455)和舒张压(r=-0.388)、夜间动态收缩压(r=-0.334)和舒张压(r=-0.265)和空腹血糖(r=-0.159)呈负相关(均P<0.05)。多因素线性回归分析结果显示,白天动态收缩压(β=-0.736)和夜间动态收缩压(β=-0.518)是CFR减少的影响因素(均P<0.05)。结论与WCHT和正常血压者比较,MHT和SHT患者的CFR明显降低,白天动态收缩压和夜间动态收缩压是CFR减少的影响因素。
出处 《中华高血压杂志》 CAS CSCD 北大核心 2016年第3期277-280,共4页 Chinese Journal of Hypertension
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参考文献13

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