摘要
阿尔茨海默病(AD)是老年期痴呆最常见类型。目前,分子影像学在AD的基础与临床研究中发挥着重要的作用。PET功能显像可通过各种显像剂敏感、特异性地反映AD的病理生理学改变,笔者将重点介绍^(18)F-FDG显像剂和淀粉样蛋白显像剂在AD中的应用,详细阐述PET显像在AD病因学研究、早期诊断、鉴别诊断、疾病转归和药物治疗中的作用。
Alzheimer's disease is the most common cause of dementia in the current elderly population. Molecular imaging plays an important role in the basic and clinical research of Alzheimer's disease. PET can detect pathophysiological changes in Alzheimer's disease with different radiotracers. This paper will focus on evaluating the value of ^18F-FDG and amyloid PET imaging in Alzheimer's disease, and describe in detail the role of PET imaging in the research of etiology, early diagnosis, differential diagnosis, prognosis and medical treatment of Alzheimer's disease.
出处
《中国临床医学影像杂志》
CAS
北大核心
2016年第5期367-369,共3页
Journal of China Clinic Medical Imaging