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基于硼替佐米的治疗方案在老年初治套细胞淋巴瘤中的应用 被引量:4

Bortezomib-Based Therapy for Newly Diagnosed Older Mantle-Cell Lymphoma Patients
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摘要 1文献来源Robak T,Huang H,Jin J,et al.Bortezomibbased therapy for newly diagnosed mantle-cell lymphoma[J].N Engl J Med,2015,372(10):944-953.2证据水平1b。3背景蛋白酶体抑制剂硼替佐米初始批准用于复发的套细胞淋巴瘤(mantle cell lymphoma,MCL)的治疗,单药治疗可提高其缓解率(response rate,RR)、无进展生存率和总生存率(overall survival,OS),
出处 《循证医学》 CSCD 2016年第2期83-85,92,共4页 The Journal of Evidence-Based Medicine
关键词 套细胞淋巴瘤 老年人 硼替佐米 mantle-cell lymphoma olderly Bortezomib
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参考文献7

  • 1Vose JM. Mantle cell lymphoma: 2015 update on diagnosis, risk- stratification, and clinical management [J]. Am JHematol, 2015, 90(8) : 739-745.
  • 2Abrahamsson A, Albertsson-Lindblad A, Brown PN, et al. Real world data on primary treatment for mantle cell lymphoma: A Nordic Lymphoma Group observational study [Jl. Blood, 2014, 124(8): 1288-1295.
  • 3Howard OM, Gribben JG, Neuberg DS, et al. Rituximah and CHOP induction therapy for newly diagnosed mantle- cell lymphoma: Molecular complete responses are not predictive of plvgression-free survival [J]. J Clin Oncol, 2002, 20 (5) : 1288-1294.
  • 4Paramore A, Frantz S. Bortezomib [J]. Nat Rev Drug Discov, 2003, 2(8) : 611-612.
  • 5Fisher RI, Bernstein SH, Kahl BS, et ah Multicenter phase ]I study of Bortezomib in patients with relapsed Qr refractory mantle cell lymphoma [J]. J Clin Oncol, 2006, 24 (30) : 4867-4874.
  • 6Goy A, Bernstein SH, Kahl BS, et al.Bortezomib in patients with relapsed or refractory mantle cell lymphoma : Updated time -to-event analyses of the muhicenter phase 2 PINNACLE study [J]. Ann Oncol, 2009, 20(3): 520-525.
  • 7Kane RC, Dagher R, Farrell A Iet al. Bortezomib for the treatment of mantle cell lymphoma [J]. Clin Cancer Res, 2007, 13( 18 Pt 1) :5291-5294.

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