人乳头瘤病毒检测临床应用误区

Misunderstanding of human papillomavirus (HPV) detection in clinical application

高危型人乳头瘤病毒(HPV)的持续感染是宫颈癌和宫颈癌前病变发生的重要原因,HPV检测有效地提高了宫颈癌筛查的敏感度,是宫颈癌筛查的重要方法。但由于HPV检测方法众多,各种检测方法的设计、原理以及临床阳性阈值设定存在差异等因素,临床应用中容易存在误区。

Persistent cervical infection with high-risk human papillomavirus （HPV） genotypes is the main cause of the development of cervical cancer and pre- eaneer.HPV detection effectively improves the sensi- tivity of cervical cancer detection and becomes an important method of cervical cancer screening.How- ever, due to wide variety of HPV detection methods, differences among various detection methods, princi- ples and clinical cut-off value and so on, clinicians tend to have some misunderstandings in their clinical application.