糖尿病足溃疡患者不同程度感染的临床治疗方案分析

Clinical treatment of diabetic foot ulcers patients with varying degrees of infections

目的探讨不同程度感染的糖尿病足溃疡患者的临床特点,制定糖尿病足溃疡感染患者的治疗方案,为临床治疗糖尿病足溃疡感染提供理论指导。方法选取2012年3月-2014年3月117例于医院接受治疗的糖尿病足溃疡感染患者作为研究对象,并根据患者的临床感染程度分为重度感染组38例、中度感染组39例、轻度感染组40例,观察3组患者的治疗效果及预后。结果糖尿病足溃疡患者随着感染程度增加,治愈时间越长,重度感染组、中度感染组及轻度感染组的愈合时间分别为(84.2±16.4)(56.2±11.9)(27.5±7.5)d;住院时间分别为(86.3±17.9)(59.1±13.5)(29.6±8.4)d;治疗费用分别为(54 678±461)(31 024±384)(23 465±296)元;随着感染程度的不断加重以及溃疡的加深,患者预后情况越差,愈合率较低,截肢率及病死率不断上升。结论糖尿病足溃疡患者随着年龄的增加,致残及死亡的概率逐渐增大,并且感染程度与溃疡的严重程度呈正比关系,影响患者的治疗效果及预后。

OBJECTIVE To investigate the clinical characteristics of the diabetic foot ulcers patients with varying degrees of infections and put forward the treatment programs so as to provide theoretical basis for clinical treatment of the diabetic foot ulcers patients with infections.METHODS A total of 117 diabetic foot ulcers patients with infections who were treated in the hospital from Mar 2012 to Mar 2014 were recruited as the study objects and divided into the severe infection group with 38 cases,the moderate infection group with 39 cases,and the mild infection group with 40 cases according to the status of clinical infections.The therapeutic effect and prognosis were observed and compared among the three groups of patients.RESULTS The healing time of the patients with diabetic foot ulcers was prolonged with the increase of degree of infections;the healing time was（84.2±16.4）days in the severe infection group,（56.2±11.9）days in the moderate infection group,（27.5±7.5）days in the mild infection group;the length of hospital stay was（86.3±17.9）days in the severe infection group,（59.1±13.5）days in the moderate infection group,（29.6±8.4）days in the mild infection group;the cost of treatment was（54678±461）yuan in the severe infection group,（31024±384）yuan in the moderate infection group,（23465±296）yuan in the mild infection group.With the continuous increase of degree of infections and worsening of ulcers,the prognosis of the patients became worse,the healing rate was relatively low,and the amputation rate and mortality rate continued to rise.CONCLUSIONThe amputation rate and mortality rate of the patients with diabetic foot ulcers are gradually increased with the age,and the degree of infections is positively correlated with the severity of ulcers,which may affect the therapeutic effect and prognosis of the patients.