6年肿瘤患者HIV感染率与感染特点分析

Prevalence rates of HIV infection in cancer patients and characteristics of infection in 6years

目的了解肿瘤患者人类免疫缺陷病毒（HIV）感染状况及特点,为临床诊治提供参考依据。方法对医院2008年1月-2013年12月138 937例肿瘤患者进行HIV抗体的检测,筛出HIV抗体阳性的肿瘤患者,采用回顾性调查对患者的临床资料进行分析;采用SPSS 16.0软件对数据进行统计分析。结果 138 937例肿瘤患者共检出HIV抗体阳性104例,阳性率0.75‰,呈逐年上升趋势;HIV抗体阳性患者肿瘤疾病以肺癌、子宫颈癌、淋巴瘤（NHL）和食管癌常见,分别占23.08%、25.96%、13.46%、8.65%;以40~50岁年龄段感染率最高,占37.5%;肿瘤患者感染途径主要是临床输血和有偿供血,分别占41.35%和18.27%。结论应针对肿瘤患者HIV感染状况和特点,采取有效的治疗手段,防止HIV病毒传播和医院感染的发生,降低HIV感染者继发恶性肿瘤的风险。

OBJECTIVE To understand the prevalence of human immunodeficiency virus（HIV）infection in cancer patients and analyze the characteristics so as to provide guidance for clinical diagnosis and treatment.METHODS The HIV antibody was tested for 138 937 cancer patients who were treated in the hospital from Jan 2008 to Dec2013,and the HIV antibody-positive tumor patients were screened out.The clinical data of the patients were retrospectively surveyed,and the statistical analysis of data was performed with the use of SPSS16.0software.RESULTS The HIV antibody was tested positive in 104 of 138 937 cancer patients,with the positive rate 0.75‰,and the positive rate showed an upward trend.Of the HIV antibody-positive cancer patients,23.08% had lung cancer,25.96% had cervical cancer,13.46% had lymphoma,and 8.65% had esophageal cancer.The infection rate was the highest in the patients aged between 40 and 45years old.Among the tumor patients with the infection,41.35% were infected through clinical transfusion,and 18.27% were infected through paid blood donation.CONCLUSIONIt is an effective way to take the treatment measures aiming at the prevalence and characteristics of the HIV infection in the tumor patients and prevent the spread of HIV and nosocomial infection so as to reduce the risk of secondary malignancies in the patients with HIV infection.