限制性输液在感染中毒性休克患者麻醉中的临床应用效果分析

Clinical effect of restrictive transfusion on treatment of anesthesia patients with toxic shock

目的探讨限制性输液在感染中毒性休克患者麻醉中的临床治疗效果,为临床治疗感染中毒性休克提供理论指导与依据。方法选取2013年2月-2015年1月于医院接受治疗的感染中毒性休克患者70例作为研究对象,将患者随机分为观察组和对照组,各35例,观察组患者应用限制性输液的治疗方法进行治疗;对照组患者应用常规补液方法;对比两组患者术后的平均动脉压、动脉血氧分压、出血量和术中输液量;比较两组患者术后机械通气时间、入住ICU时间、急性呼吸窘迫征、多器官功能障碍征的发生率和病死率差异;采用SPSS17.0软件进行统计分析。结果两组患者术后平均动脉压差异无统计学意义;两组患者动脉血氧分压、输液量和出血量比较差异有统计学意义(P<0.05);两组患者术后机械通气时间、入住ICU时间、急性呼吸窘迫征、多器官功能障碍征发生率和病死率比较差异均有统计学意义(P<0.05)。结论限制性输液治疗感染中毒性休克患者,能给其身体各器官起到很好的保护作用,更有效的给各个器官输送氧气,降低术后并发症的发生率,提高患者身体各项机能,改善患者预后,提高患者的治愈率。

OBJECTIVE To explore the clinical effect of restrictive transfusion on treatment of anesthesia patients with toxic shock so as to provide theoretical basis for clinical treatment of toxic shock.METHODS A total of 70 patients with toxic shock who were treated in the hospital from Feb 2013 to Jan 2015 were recruited as the study objects and randomly divided into the observation group and the control group,with 35 cases in each.The observation group was treated with restrictive transfusion,while the control group was given the conventional infusion.The postoperative average blood pressure,arterial partial pressure of oxygen,blood loss volume,and intraoperative infusion volume were compared between the two groups of patients;the postoperative mechanical ventilation duration,ICU stay,incidence rates of acute respiratory distress syndrome and multiple organ dysfunction syndrome,and mortality rates were compared between the two groups of patients,and the statistical analysis was performed with the use of SPSS17.0software.RESULTS There was no significant difference in the postoperative average blood pressure between the two groups of patients;there was significant difference in the arterial partial pressure of oxygen,infusion volume,or blood loss volume between the two groups（P〈0.05）.There was significant difference in the postoperative mechanical ventilation duration,ICU stay,incidence rate of acute respiratory distress syndrome or multiple organ dysfunction syndrome,or mortality rate between the two groups of patients（P〈0.05）.CONCLUSION The restrictive transfusion,as is used for the treatment of the patients with toxic shock,shows protective effect on the organs,effectively delivers oxygen to the organs,reduces the incidence of postoperative complications,improve the body functions and prognosis of the patients,and raise the cure rate.