摘要
冠状动脉支架是冠状动脉血运重建最主要的治疗方式,虽然药物涂层支架被广泛应用,但支架内再狭窄仍是术后最主要的并发症。与冠状动脉造影相比,冠状动脉计算机断层扫描血管成像(CCTA)具有无创等优点而被临床所接受。虽然它评估支架再狭窄有较高的阴性预测值,但有辐射,并且受空间分辨率的限制,导致其诊断准确率不高。近来部分学者提出低剂量CCTA、高分辨率CT、冠状动脉管腔内密度阶差征以及心肌灌注与CCTA相结合的一种新型检查方法来解决以上问题。
Coronary stenting is currently the mostly applied method for coronary revascularization. Despite of the wide application of drug eluting stents, in-stent restenosis (ISR) remains as a main problem after stent implantation. Compared with invasive coronary angiography, coronary computed tomography angiog- raphy(CCTA) emerged as a non-invasive method in the follow-up of patients after coronary revascularization. According to previous studies,it has a high negative value for ruling out ISR. However, the related radiation exposure remains as major concern. Moreover,the diagnostic accuracy is restricted mostly due to the limited spatial resolution. To overcome above defects,recent studies are focusing on low-dose coronary CT angiogra- phy, high definition CT, intracorenary transluminal attenuation gradient and "one-stop shop" imaging protocol which combined myocardial CT perfusion with CCTA.
出处
《医学综述》
2016年第9期1730-1733,共4页
Medical Recapitulate
基金
国家自然科学基金(81301219)
上海市科研技划项目(13ZR1431400)