超声引导下甲状腺结节细针穿刺抽吸活检术后出血原因分析

Analysis of risk factors of hemorrhage after ultrasound-guided thyroid nodules fine needle aspiration biopsy

目的:探讨超声引导下甲状腺结节细针穿刺抽吸活检(US-FNAB)术后局部出血发生的原因。方法:对2012年9月至2014年9月行甲状腺单发结节US-FNAB的708例病人进行回顾性分析,根据术后有无出血分为两组,评估术后发生出血与甲状腺结节特征及穿刺时操作情况的相关性。结果:甲状腺结节US-FNAB后出血发生率为8.6%(61/708)。结果表明结节部位、病灶与包膜接触、甲状腺实质血流增多及操作者经验与术后出血相关(P<0.05)。结论:甲状腺结节US-FNAB是一种安全的活检方法,控制相关危险因素将有效降低US-FNAB术后出血的发生。

Objective To analyze the risk factors of hemorrhage after ultrasound-guided fine needle aspiration biopsy （US-FNAB） for thyroid nodules. Methods The data of 708 patients with US-FNAB for single thyroid nodule from Sep 2012 to Sep 2014 were retrospectively analyzed. The patients were divided into bleeding group and without bleeding groups. The correlation of postoperative hemorrhage with characteristics of the nodules and the procedure of US-FNAB between 2 groups was studied. Results The incidence of hemorrhage after US-FNAB was 8.6% （61/708}. It was suggested that the associated risk factors of postoperative hemorrhage were location of nodules, the nodules contacting with thyroid capsule, increased blood supply of thyroid and operator experience （P〈0.05）. Conclusions US-FNAB is a safe diagnostic tool to assess thyroid nodules. Awareness of associated risk factors by operators could reduce the incidence of hemorrhage after US-FNAB.