高血压病肝气郁结证证治规律探讨

Exploration on laws of diagnosis and treatment of hypertension with liver-qi stagnation syndrome

肝气郁结是高血压病早期最多见的重要病机,临床常见眩晕、头痛、头目不清利、胸胁胀痛、抑郁寡欢、善太息、脉弦等表现。现代研究显示,该病与机体抗氧化酶活力降低、血微量元素下降、脂质代谢异常、血清雌二醇、卵泡刺激素、孕酮等激素水平异常以及精神因素影响等密切相关,其证治规律遵循中医辨证论治的基本原则,具体治法以疏肝解郁为要,兼以清火、理气、活血等法辅之。临床文献显示,以疏肝解郁法为主治疗高血压病疗效确切,在中医证候得到缓解的同时,患者相应的生化检测指标也有改善,从而为明确疏肝解郁为高血压病早期肝气郁结证的主要治法提供了微观理论依据。

Liver-qi stagnation is an important pathological basis of hypertension. Its essence is closely related to the following body＇s abnormal hormone levels：i, e. reduced antioxidant enzyme activity, decreased blood trace el- ements, mental factors, abnormal lipid metabolism, serum estradiol, follicle stimulating hormone, progesterone etc. Its syndrome manifestations have inherent laws. Its treatment should be mainly dispersing stagnated liver-qi to relieve qi stagnation with clearing away fire, regulating qi and promoting blood circulation etc.