疏风通络方对支气管哮喘急性发作期呼出气一氧化氮值的影响

Observation on effect of shufeng tongluo formula on FeNO values during acute attack of bronchial asthma

目的:观察疏风通络方对支气管哮喘急性发作期呼出气一氧化氮(FeNO)值的影响。方法:将52例支气管哮喘急性期患者随机分为治疗组26例和对照组26例,对照组予抗炎解痉治疗,治疗组在对照组治疗的基础上予中药汤剂疏风通络方治疗,治疗两周后比较两组患者FeNO数值的变化。结果:两组患者治疗后Fe NO值均有所下降,对照组治疗前后下降数值无显著性差异(P>0.05),治疗组治疗前后下降更明显(P<0.05),而且两组下降的幅度组间比较有显著性差异(P<0.05)。结论:疏风通络方可显著减低支气管哮喘急性发作期患者气道炎性介质一氧化氮(FeNO)数值,对抑制哮喘气道炎症有较好作用。

Objective： To observe the effect of shufeng tongluo formula on FeNO valuesduring acute attack of bronchial asthma. Methods ：52 cases of patients with acute attack of bronchial asthma were randomly divided into two groups, 26 cases in treatment group, 26 cases in control group The control group was treated with anti-inflam- matory antispasmodic. The treatment group were treated with Chinese medicine decoction of shufeng tongluo formu- la on the basis of treatment of control group. The changes of FeNO values of patients in two groups were compared after treatment of two weeks. Results ： Patients^FeNO values in both groups were decreased after treatment. The re- duced FeNO values of control group before and after treatment had not significant differences （ P 〉 0. 05 ）, while the reduced FeNO values of treatment group before and after treatment had more significant differences （ P 〈 0.05 ） . There were significant differences in lowered degree of FeNO values between two groups （ P 〈 0. 05 ）. Conclusion ： shufeng tongluo formula can significantly reduce FeNO values of patients with acute attack of bronchial asthma, and has a significant effect on the inhibition of airway inflammation of bronchial asthma.