多层螺旋CT对胃癌局部侵袭性与血流动力学相关性的研究

Study on the correlation between local invasion and haemodynamics of the gastric cancer with multi-slice spiral CT

目的探讨多层螺旋CT对胃癌局部侵袭性与血流动力学及其相关性的评价。方法 79例患者经病理证实,依据第7版AJCC胃癌分期指南南2名放射科医师行胃癌术前T分期,计算每名阅片者对胃癌T分期的准确度及总体准确度。采用体部灌注扫描序列对患者灌注扫描,分析T分期与血流量(BF)、血容量(BV)、平均通过时间(MTT)、表面通透性(PS)的差异及其相关性。结果 CT成像检出全部79例胃癌中的78例(98.7%),阅片者1与阅片者2对胃癌总体T分期诊断准确度分别为92.4%和96.2%;胃癌T分期与BV、MTT和PS有明显相关性。结论胃癌局部侵袭性与BV、MTT和PS有明显相关性。

Objective To explore the relationship between local invasion and haemodynamics of gastric cancer by multi-slice spiral CT. Methods 79 patients with pathologically confirmed as gastric cancer were staged preoperatively by two radiologists according to the 7 th edition of the AJCC cancer staging guidelines, the accuracy of gastric cancer T staging for each pathologist and overall accuracy were calculated. The difference and the correlation between gastric cancer T staging system and the parameters of CT perfusion including blood volume （BV）, blood flow （BF）, mean transit time （MTT） and permeability surface （PS） were analyzed with the CT perfusion body tumor software. Results CT imaging detected 78 cases of gastric cancer in 79 patients with detection rate of 98.7%, the diagnostic accuracies of total gastric cancer T staging for two pathologist were 92.4% and 96.2% respectively. T staging of gastric cancer was significantly correlated with BV, MTT and PS. Conclusion The local invasion of gastric cancer was significantly correlated with BV, MTT and PS.