交通伤所致重型颅脑损伤患者预后的临床影响因素分析

Analysis of the influence factors for the prognosis of severe traumatic brain injury patients caused by traffic injuries

目的分析交通伤所致重型颅脑损伤患者预后的影响因素。方法回顾性分析2012-03-2014-04我院收治的108例交通伤所致重型颅脑损伤患者的临床资料,根据格拉斯哥预后评分(GOS)分为预后不佳组和预后良好组,对年龄、性别、收缩压、血氧饱和度、血糖、瞳孔评分、损伤严重度评分(ISS)、格拉斯哥昏迷评分(GCS)等可能的影响因素进行单因素分析,并对单因素分析结果中的危险因素进行多因素Logistic回归分析。结果单因素分析结果提示,血氧饱和度、收缩压、血糖、瞳孔评分、ISS评分、GCS评分与患者预后有关,P<0.05;多因素Logistic回归分析提示,血糖、血氧饱和度、ISS评分、GCS评分为影响预后的独立危险因素,P<0.05。结论交通伤所致重型颅脑损伤患者的预后与血糖、血氧饱和度、ISS评分、GCS评分具有密切关系,重点关注、针对性改善这些指标对改善此类患者的预后具有重要意义。

Objective To analyze the influence factors for the prognosis of severe traumatic brain injury patients caused by traffic injuries. Methods A total of 108 severe traumatic brain injury patients caused by traffic injuries who were selected in our hospital from March 2012 to April 2014 were retrospective analyzed, and were divided into good prognosis group and poor prognosis group according to the Glasgow outcome scale （GOS）. The possible influencing factors were analyzed by univariate analysis, such as the patient＇s age, sex, systolic blood pressure, oxygen saturation, blood glucose, pupil score, injury severity score （ISS）, Glasgow coma score （GCS） and other single factor, and the risk factors ：were analyzed by multivariate Logistic regression analysis. Results Univariate analysis showed that the oxygen saturation, systolic blood pressure, blood sugar, pupil scores, ISS score and GCS score were related to the prognosis of patients, P〈0.05. Multivariate Logistic regression analysis showed that blood glucose, oxygen saturation, ISS score, GCS score were independent risk factors, P〈0.05. Conclusion The prognosis of severe traumatic brain injury patients caused by traffic injuries are closely related to glucose, oxygen saturation, ISS score, GCS score. Focusing on and targeting to improve these indicators is important to improve the prognosis.