肾康注射液联合尿毒清颗粒保留灌肠治疗慢性肾衰竭的临床疗效

Shenkang injection and niaoduqing granule combination therapy for chronic renal failure

目的观察肾康注射液联合尿毒清颗粒保留灌肠来治疗慢性肾衰竭患者的临床疗效。方法将我院2012年1月-2014年12月收治的107例慢性肾衰竭患者随机分成观察组（56例）和对照组（51例）,对照组患者给予常规治疗,而观察组患者使用肾康注射液及尿毒清颗粒保留灌肠。记录比较治疗前后患者的临床症状积分,肾功能变化,以及血红蛋白（Hb）、血清白蛋白（Alb）、血尿酸（BUA）的变化。结果观察组治疗后的临床症状积分显著低于对照组（P〈0.05）。并且观察组治疗后血肌酐（Scr）、尿素氮（BUN）指标显著低于对照组（P〈0.05）,而GFR、血红蛋白、血清白蛋白水平显著高于对照组（P〈0.05）。观察组总有效率为80.4%,显著高于对照组52.9%（P〈0.05）。结论肾康注射液联合尿毒清颗粒保留灌肠治疗慢性肾衰竭有很显著的疗效,能有效缓解患者症状,延缓肾衰进展,改善贫血和营养不良状况。

Objective To integrative clinical efficacy of Shenkang injection combined with Niaoduqing granule in treatment of chronic renal failure. Methods 107 patients with this disease treated in the hospital from January 2012 to December 2014 were randomly divided into observed group（56 cases） and control group（51 cases）,patients in control group only received routine treatment, while others received Shenkang injection and Niaoduqing granule combination therapy.The clinical symptom score, renal function, hemoglobin, serum albumin, serum uric acid were compared. Results After the treatment of drug combination,the clinical symptom score of observed group were lower than those of the control group（P〈 0.05）;the Scr, BUN level of observed group were lower than those of the control group（P〈 0.05）;the GFR Hb, Alb level of observed group were higher than those of the control group（P〈 0.05）;the total efficiency of 80.4% in observed group was significantly higher than that of 52.9% in control group（P〈 0.05）. Conclusion The treatment of chronic renal failure with Shenkang injection combined with Niaoduqing granule has a significant effect, and can effectively alleviate the symptoms of patients, delay renal failure progress, improve anemia and malnutrition.