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大脑突触外GABA_A受体功能与女性生殖周期相关抑郁症 被引量：4

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摘要 生殖周期中雌激素和孕激素等类固醇激素的波动会影响大脑和诱发精神症状,甚至导致严重的抑郁症和焦虑症。目前的神经药理学研究证实,特定的脑区的抑制性神经递质突触外受体-伽马氨基丁酸A型受体(GABA_A)很有可能与此类经期综合症的发生相关。突触外GABA_A受体产生强直电导可直接调控特定脑区神经元群体的兴奋性。本文着眼于现有研究并结合我们的实验结果,以期阐述大脑突触外GABA_A受体功能与女性生殖周期相关抑郁症的关系。
作者 郑小敏 吴凯(综述) 王燕蓉 赵承军(审校)
机构地区 宁夏医科大学生育力保持教育部重点实验室 赫尔辛基大学生物医学中心药理系
出处 《现代妇产科进展》 CSCD 北大核心 2016年第4期314-316,共3页 Progress in Obstetrics and Gynecology
关键词 GABA 突触 GABA受体 经期综合征 抑郁
分类号 R711.6 [医药卫生—妇产科学]
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参考文献30

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二级参考文献9

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现代妇产科进展
2016年 第4期

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