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基于石墨烯场效应晶体管免疫传感器医学检测中应用的探讨 被引量:3

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摘要 免疫检测方法种类繁多,在医学检测中有一定应用,然而传统方法存在某些亟待改进的地方。随着纳米技术和电子技术迅猛发展,生物传感器开始被用于医学检测中。其中,基于石墨烯场效应晶体管(FET )免疫传感器由于灵敏性和特异性高、反应快、免标记等优势已开始应用于医学检测中。自第1个生物传感器发明[1],科学家对于生物传感器研究越发热门,并发表大量相关文献。其中,免疫传感器作为生物传感器引起广泛重视。近年来,随着纳米技术和现代电子技术迅猛发展,基于石墨烯FET用于制备免疫传感器吸引了广泛研究,并已被用于检测各种生物分子。传统免疫检测方法包括放射免疫法、酶标免疫法、化学免疫发光法、荧光免疫法等,上述方法灵敏性和特异性不高,需要荧光或放射性元素标记,操作复杂,耗时长[2]。基于石墨烯FET免疫传感器与传统检测方法相比,在灵敏性和选择性上都占一定优势,且不需要标记,分析速度快,试剂消耗少,非常适用于生物分子检测,可预见其未来将在医学检测中发挥更大作用。
作者 蔡冰洁 李艳
出处 《检验医学与临床》 CAS 2016年第9期1283-1285,共3页 Laboratory Medicine and Clinic
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参考文献21

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