ST段抬高心肌梗死818例临床资料对比分析

Comparative analysis of clinical data from 818 cases of patients with ST segment elevation myocardial infarction

目的:探究2006年与2014年我院收治ST段抬高心肌梗死患者一般资料、主要用药、住院期间不良心血管事件发生率的变化情况。方法:将我院2006年和2014年全部ST段抬高心肌梗死患者分为2006年组(n=96例)和2014年组(n=722例),对2组临床资料进行回顾性分析并比较。结果:2014年组与2006年组相比,合并吸烟史、氯吡格雷、血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂(ACEI/ARB)/螺内酯应用及急诊冠脉介入治疗比例升高,住院期间再发心绞痛、心源性死亡比率下降,阿司匹林、他汀类药物使用率及发病到就诊时间、住院天数无明显变化。结论:吸烟与急性心肌梗死发病率升高关系密切。患者对急性心肌梗死知识仍然缺乏,医生对RAAS抑制剂重视程度不够。

Objective： To explore the changes of general data including the main medication and the adverse cardiovascular events occurred in the inpatients with ST segment elevation myocardial infarction in our hospital in 2006 and 2014. Methods： The patients with ST segment elevation myocardial infarction were divided into a 2006 group （n=96 cases） and a 2014 group （n=722 cases）. The clinical data from these two groups were retrospectively analyzed and compared. Results： The ratios of the patients with smoking history, taking clopidogrel, angiotensin converting enzyme inhibitors/angiotensin receptor blocker （ACEI/ARB）/spironolactone and undergoing emergency percutaneous coronary interventional increased while the rates of recurrent angina pectoris and cardiac death decreased in the 2014 group. There were no significant changes in the rates of taking aspirin and statins and the time from onset to treatment and the length of hospital stay between the two groups. Conclusion： Smoking is closely related to the incidence of acute myocardial infarction. Patients still lack the related knowledge of acute myocardial infarction and doctors should further pay great attention to the use of RAAS inhibitors.