红肉摄入量对中老年人铁蛋白水平的影响分析

Effect of Red Meat Intake on Serum Ferritin Levels in Middle Aged and Elderly Population

目的：探讨中老年人红肉的膳食摄入情况,分析红肉摄入量与血清铁蛋白水平的相关性,并研究红肉摄入与中老年人患铁过载的风险的关系。方法：以参加体检的年龄在40~85岁的515名中老年人为研究对象,以血清铁蛋白作为铁营养状况指标,采用半定量食物频率法进行膳食调查,将居民的红肉摄入量和铁蛋白含量作相关性分析,并对居民红肉的摄入频率与铁过载之间的风险进行多因素Logistic回归分析。结果：在研究的中老年人群中,红肉摄入量与血清铁蛋白呈正相关。按四分位红肉摄入量为≤20.0g/d、20.0~42.9g/d、42.9~85.7g/d、〉85.7g/d分组,各组中老年人血清铁蛋白中位数分别为60.9、67.1、80.4、100.4μg/L。调整性别、年龄、BMI、吸烟、饮酒等多种混杂因素后,红肉每周摄入≥7次的中老年人群发生铁过载的风险显著高于每周摄入红肉≤4次的人群,OR为3.36（95%CI：1.18,9.55,P〈0.05）。结论：在中老年人群中,过量摄入红肉可增加机体发生铁过载的风险,个体膳食模式可能是高铁储量的重要调节因素。

【Objective】To study the dietary intake of red meat in middle aged and elderly population to analyze the correlation between red meat intake and serum ferritin levels,and the relationship between red meat intake and the risk of iron overload in the middle aged and elderly population.【Method】Among 515 middle-aged and elderly people aged 40 ~ 85 years old who participated in the physical examination,serum ferritin was used as an indicator of iron nutritional status,and we carried out dietary survey using semi quantitative food frequency questionnaire. We analyzed the correlation between red meat intake and ferritin levels and assessed the relation between red meat and the risk of high iron stores by Multivariate Logistic Regression analysis.【Result】The red meat intake was positively correlated with serum ferritin levels in the studied middle and elderly aged people. According to the quartile of intake of red meat including ≤20g / d,20. 0 ~42. 9g / d,42. 9 ~ 85. 7g / d, 〉 85. 7g / d,the median of serum ferritin was 60. 9,67. 1,80. 4,100. 4μg / L,respectively. The risk of high iron stores was significantly higher in subjects who consumed ≥7 times of red meat than in those who consumed ≤4 times per week,（ ORs：3. 36; 95% CI： 1. 18,9. 55, P 〈 0. 05）, after adjusted for gender, age, BMI, smoking, drinking and other confounding factors.【Conclusion】Intakes of red meat promoted high iron stores in the middle and elderly aged population and individual dietary patterns might be important modulators of high iron stores.