摘要
抗生素干粉吸入剂可实现肺部高剂量给药,且全身性不良反应发生率低,给药时间短,使用方便。目前,已有两种抗生素干粉吸入剂获批用于治疗合并铜绿假单胞菌感染的肺部囊性纤维变性。本文简要综述抗生素干粉吸入剂的临床应用和研究进展。
Dry powder inhaler （DPI） antibiotics has some advantages including high drug doses in lungs, low systemic side effects, relatively shorter durations of administration, and easy to use. Currently, two DPI antibiotics have been approved for the treatment of pulmonary cystic fibrosis with Pseudomonas aeruginosa infection. This review describes progress on research and clinical application of DPI antibiotics.
出处
《世界临床药物》
CAS
2016年第5期348-351,共4页
World Clinical Drug
关键词
干粉吸入剂
抗生素
颗粒工程
dry powder inhaler （DPI）
antibiotic
particle engineering
