2012年江苏省句容市农村地区居民高三酰甘油腰围表型流行现状及危险因素

Prevalence and risk factors of hypertriglyceridemic waist phenotype in rural residents in Jurong City,Jiangsu Province,2012

目的了解江苏省某地农村居民高三酰甘油腰围表型（ hypertriglyceridemic waist phenotype, HTWP ）的流行现状，并探讨其主要危险因素。方法采用横断面研究方法，于2012年10-11月对江苏省句容市各镇多阶段随机抽出的5626名农村居民开展腰围与血清三酰甘油（TG）的测量与实验室检测，并开展问卷调查，利用t检验、方差分析等分析不同表型组特征差异，并采用非条件logistic回归模型筛选HTWP的独立危险因素。结果共有741名（13．17％）农村居民患有HTWP，在调整了年龄、性别、婚姻状况等混杂因素后，采用logistic回归模型分析出体力劳动职业类型（OR=1．360，CI：1．128～1．638，P=0．001），超重与肥胖（OR=3．247，CI：2．888-3．650，P〈0．001），高血压病（OR=1．826，CI：1．529—2．181，P〈0．001）以及高胆固醇血症（OR=1．815，CI：1．408～2．340，P〈0．001）为HTWP发病的独立危险因素。结论2012年江苏省句容市农村居民高三酰甘油腰围表型具有较高的流行率，其主要的独立危险因素包括体力劳动职业类型、超重与肥胖、高血压病以及高胆固醇血症，应加强对HTWP这一表型以及其影响因素的控制，同时应关注HTWP导致的其他慢性病。

Objective To investigate the prevalence of hypertriglyceridemic waist phenotype （ HTWP ） and its main risk factors in rural residents in Jurong City, Jiangsu Province, 2012. Methods With a multistage sampling method, 5,626 rural residents were chosen from towns in Jurong City, Jiangsu Province to complete the cross-sectional study during October and November, 2012. Waist circumference was measured, serum triacylglycerol was tested, and a questionnaire survey was conducted. The characteristic differences among different triaeylglycerol-waist phenotypes were analyzed using t-test and ANOVA. The independent risk factors of HTWP were screened by unconditional logistic regression model. Results A total of 741 residents （ 13.17% ） suffered from HTWP. After the confounding factors like age, sex and marital status were adjusted, the risk factors for HTWP screened by logistic regression model were profession type of manual labor （OR = 1.360, CI： 1.128- 1.638 ,P= 0.001 ） , overweight and obesity （ OR = 3.247, CI： 2.888 - 3.650, P〈0.001） , hypertension （ OR = 1.826, CI： 1.529 - 2.181, P〈0.001 ） and hypercholesterolemia （OR= 1.815,CI：1.408-2.340,P〈0.001）. Conclusions HTWP is prevalent in rural residents in Jurong City, Jiangsu Province, 2012. Its main risk factors are profession type of manual labor, overweight, hypertension and hypereholesterolemia. Prevention and control of the HTWP phenotype and its risk factors should be strengthened and other chronic diseases caused by HTWP should be concerned.