摘要
本文概述了现代细胞工程学在细胞基因组学上的应用。通过非侵入法获得颊黏膜细胞,观察细胞基因组遗传学损伤和细胞动力学指标的改变来对人类群体和个体的健康状况进行监测。这与当代医学倡导的4P模式,即预防性(preemptive)、预测性(predictive)、个体化(personalized)和参与性(participatory)一致。
This paper reviews the application of modern cell engineering to cell genomics. Buccal mucosa cells is obtained by non-invasive techniques for the investigation of genome. The health of human population and individuals is monitored by observing the changes of the cytogenetic damages and cell kinetics indexes. It is in accordance with the 4P model （ preemptive, predictive, personalized and participatory） promoted by the modem medical science.
出处
《实用预防医学》
CAS
2016年第6期766-768,共3页
Practical Preventive Medicine
关键词
多器官细胞标本
细胞核损伤
微核
增生
变异
监测
4P模式
Muhiorgan cell specimen
Nuclear damage
Micronucleus
Proliferation
Mutation
Monitoring
4P Model
