温阳化癥粉对家兔多次皮肤刺激性试验的研究

Study on the Wenyanghuazheng powder to rabbit's multiple skin irritation test

目的对温阳化癥粉进行动物多次皮肤刺激试验,为其临床使用提供安全评价。方法将温阳化癥粉涂抹于家兔完整皮肤上,每天1次,连续涂抹14d,每天观察症状表现。结果温阳化癥粉对家兔多次皮肤刺激试验的皮肤反应积分均值为1.70分,温阳化癥粉对家兔的皮肤刺激属轻刺激。结论温阳化癓粉外敷皮肤具有一定的安全性,但长期使用可能对被使用者造成不良影响。

Objective To do the skin irritation test of the multiple animal for clinical drug safety evaluation of Wenyanghuazheng powder.Methods The Wenyanghuazheng powder was onto the rabbit intact skin of once a day,and continuously applied 14 days.The rabbit skin symptoms observed in every day.Results rabbit was tested by Wenyanghuazheng powder to multiple skin irritation that the skin reaction average of 1.70 points.Conclusions This Wenyanghuazheng powder of rabbit skin irritation test belong to light stimulation.If use for Wenyanghuazheng powder a long time,is likely to be the user have a negative effect.