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纤维连接蛋白EDA片段功能及临床应用前景研究进展 被引量：2

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摘要 蛋白结构域A（extra domain A,EDA）是纤维连接蛋白（fibronectin,FN）的可剪切结构域之一,在机体的胚胎发育、血管生长、细胞迁移及细胞分化中发挥重要作用,与肿瘤、纤维化、血栓等多种疾病相关。现就EDA的结构、生物学功能以及EDA临床应用研究进展综述如下。1 EDA的结构与位置FN是构成细胞外基质（extracellular matrix,ECM）的一种大分子糖蛋白,FN有2种形态,
作者 蔡晶晶 王雅洁 严继贵
机构地区 安徽医学高等专科学校药学系生物制药教研室
出处 《河北医科大学学报》 CAS 2016年第5期617-620,共4页 Journal of Hebei Medical University
基金 安徽省高校自然科学研究项目(KJ2015A420)
关键词 纤连蛋白类 EDA片段 综述文献
分类号 R341.22 [医药卫生—基础医学]
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参考文献26

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二级参考文献40

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河北医科大学学报
2016年 第5期

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