安徽阜阳冬季手足口病患者合并病毒感染的调查研究

Co-infected viruses in HFMD patients of Anhui Fuyang in 2013

目的 研究安徽阜阳2013年冬季手足几病患儿合并其他病毒感染情况.方法 根据手足口病病例诊断标准诊断收集2013年11月-2013年12月安徽阜阳手足口病住院病例及资料,采集患儿血清.使用酶联免疫吸附试验（ELISA）方法检测血清标本中的细小病毒B19、I型单纯疱疹病毒、巨细胞病毒、腺病毒、呼吸道合胞病毒和副流感病毒的IgM抗体.整理分析患儿合并病毒感染情况.结果 2013年11月-2013年12月45份手足口病患儿血清腺病毒IgM阳性30例（67.7％）,呼吸道合胞病毒IgM阳性8例（17.8％）,细小病毒B19 IgM阳性8例（17.8％）,巨细胞病毒IgM阳性3例（6.7％）,单纯疱疹病毒IgM阳性l例（2.2％）,血清中未检测出现副流感病毒IgM抗体.同时发现多例合并两种以上病毒IgM阳性现象.结论 2013年阜阳地区冬季手足口病合并腺病毒、呼吸道合胞病毒和细小病毒B19等为主的感染.

Objective To study the children HFMD co-infected with 6 viruses in Fuyang of AnhuiProvince in the winter of 2013.Methods Forty-five serum samples of HFMD hospitalized cases werecollected according to the diagnostic criteria of HFMD in Fuyang from November 2013 to December 2013.Serum IgM of ADV,RSV,B19,HCMV,HPIVs,and HSV were detected with ELISA method.ResultsThirty cases（67.7%） co-infected with ADV,8 cases （17.8%） co-infected with RSV,8 cases （17.8%）co-infected with parvovirus B19,3 cases （6.7%） co-infected with HCMV,1 case （2.2%） co-infectedwith HSV among 45 samples were found in 45 HFMD cases from November 2013 to December 2013.NoHPIVs IgM was detected in these samples.Two or more viruses＇ co-infections in HFMD also were found inthis study.Conclusion Co-infected viruses in HFMD cases are mainly ADV,RSV,and B19 in Fuyang in2013 winter.