钬激光联合微创经皮肾镜取石术治疗肾结石疗效及安全性评价

The Efficacy and Safety Evaluation of Holmium Laser and Minimally Invasive Percutaneous Nephrolithotomy in the Treatment of Kidney Stones

目的探讨分析在肾结石治疗中使用钬激光联合微创经皮肾镜取石术的临床效果,并对其安全性进行评价。方法选取来我院就诊的肾结石患者112例,随机分为常规组56例,使用传统的经皮肾镜取石术进行治疗;试验组56例,使用钬激光联合微创经皮肾镜取石术进行治疗,观察两组患者治疗的临床效果及并发症发生情况。结果试验组患者的住院时间及手术时间均较常规组的患者缩短,差异有统计学意义(P<0.05);试验组患者的术中出血量显著少于对照组,差异有统计学意义(P<0.05)。试验组患者在手术后7d、1个月、3个月的结石清除率要显著优于常规组患者,差异有统计学意义(P<0.05);经过不同治疗后,试验组患者的清石次数要显著少于常规组,差异有统计学意义(P<0.05)。试验组患者的BUN、SCr水平要较常规组患者的BUN、SCr水平显著降低,两者的差异有统计学意义(P<0.05)。试验组患者并发症发生率要显著少于常规组患者并发症发生率,差异有统计学意义(P<0.05)。结论钬激光联合微创经皮肾镜取石术对肾结石患者的治疗具有较明显的治疗效果,并且安全性较高,在临床治疗中应积极的使用。

Objective To discuss the efficacy and safety evaluation of Holmium laser and minimally invasive percutaneous nephrolithotomy in the treatment of kidney stones. Methods Selected 112 cases of patients to our hospital with kidney stones,randomly divided 56 patients into group of using conventional percutaneous nephrolithotomy surgery for treatment; 56 cases in the intervention group,the use of holmium laser and minimally invasive percutaneous nephrolithotomy surgery performed treatment,patients in both groups observed clinical effects and occurrence of complications. Results Hospital stay and operation time of the patients in the intervention group were significantly shortened compared with the conventional group（ P〈0. 05）; Patients in the intervention group blood loss was significantly less than the conventional group（ P〈0. 05）. Patients in the intervention group,stone clearance rate of 7days after surgery,one month,three months was significantly better than the conventional group patients（ P〈0. 05）; Stone clearance times of the patients in the intervention group was significantly less than the patients in the conventional group after treatment（ P〈0. 05）. BUN,SCr levels of the patients in the intervention group compared to the conventional group patients were significantly reduced（ P〈0. 05）. The incidence rate of complications in the intervention group was significantly less than that in the routine group（ P〈0. 05）. Conclusion Holmium laser and minimally invasive percutaneous nephrolithotomy for renal calculi patients has more obvious treatment effect and high safety,which should be actively used in the clinical treatment.