改进处方点评方法对促进Ⅰ类切口预防性抗菌药物合理使用的效果分析

Effect analysis of the preventive use of antibiotics in improving type I incision by the modified prescription comment

目的:探讨改进处方点评方法对Ⅰ类切口手术预防使用抗菌药物的影响。方法:随机抽取改进方法前后的Ⅰ类切口手术出院病历,对其预防使用抗菌药物的合理性进行对照分析。结果:通过改进处方点评方法,Ⅰ类切口预防性抗菌药物使用率由48.3%下降至31.6%(P<0.01),抗菌药物合理使用率由57.5%提高至92.0%(P<0.01),Ⅰ类切口围手术期预防使用抗菌药物选择品种的合理率由74.5%上升至87.3%(P<0.01)。结论:改进处方点评方法显著降低了Ⅰ类切口预防性抗菌药物的使用率,提高了其合理率,对保障用药安全、提高医生的用药意识具有积极意义。

Objective： To explore the effects of preventive use of antimicrobial agents on improving type Ⅰ incision by modified prescription comment. Methods： The medical records of type Ⅰ incision surgery were randomly selected. The rationality of preventive use of antimicrobial agents was contrastively analyzed by the before and after modified method of prescription comment. Results： Using the modified prescription comment,the utilization rate of the preventive use of antimicrobial agents in type Ⅰ incision decreased from48. 3% to 31. 6%（ P〈0. 01）,the reasonable use rate of antimicrobial drug increased from 57. 5% to 92%（ P〈0. 01）,and the reasonable use rate of the preventive use of antibiotics in perioperative type Ⅰ incision increased from 74. 5% to 87. 3%（ P〈0. 01）.Conclusions： The modified prescription comment can significantly decrease the utilization rate and increase the reasonable rate of the preventive use of antimicrobial agents in type Ⅰ incision,which plays the active role in ensuring medication safety and improving the consciousness of use drug.