老年男性冠心病患者血清总胆固醇水平与其病死率的相关性探讨

Correlation analysis of the serum total cholesterol level with mortality in elderly male patients with coronary heart disease

目的：探讨血清总胆固醇的水平与老年男性冠心病患者病死率的相关性。方法：208例老年男性冠心病患者按照血清总胆固醇的检测结果分为A组（血清总胆固醇〈4.16 mmol/L）、B组（血清总胆固醇4.16～〈4.68 mmol/L）、C组（血清总胆固醇4.68～〈5.2 mmol/L）和D组（血清总胆固醇〉5.2 mmol/L）。同时对患者进行血清三酰甘油水平检测和体格检查,记录年龄、体质量指数和死亡情况。结果：4组患者血清总胆固醇水平差异均有统计学意义（P〈0.01）;A组和D组病死率均高于B组,D组病死率亦高于C组（P〈0.05）;A组和D组、B组和C组的病死率差异均无统计学意义（P〉0.05）。4组患者年龄、体质量指数和三酰甘油水平差异均无统计学意义（P〉0.05）。血清总胆固醇水平〈4.16 mmol/L或〉5.20 mmol/L均可增加老年男性冠心病患者的病死率。结论：老年男性冠心病患者的血清总胆固醇水平和病死率有紧密的相关性,血清总胆固醇水平过高或过低均为引起老年男性冠心病患者病死的危险因素。

Objective： To explore the correlation of the serum total cholesterol level with mortality in elderly male patients with coronary heart disease. Methods： Two hundred and eight elderly male patients with coronary heart disease were divided into the group A（ serum total cholesterol 4. 16 mmol/L）,group B（ 4. 16 mmol/L≤serum total cholesterol 4. 68 mmol/L）,group C（ 4. 68 mmol/L≤serum total cholesterol 5. 20 mmol/L） and group D（ serum total cholesterol 5. 20 mmol/L） according to the serum total cholesterol levels. The serum triglyceride level,physical examination,age,body mass index and mortality in all patients were analyzed.Results： The differences of the serum total cholesterol levels between four groups were statistically significant（ P〈0. 01）. The mortalities in group A and D were higher than that in group B,and the mortality in group D was higher than that in group C（ P〈0. 05）.The differences of the mortalities in group A group D and group B group C were not statistically significant（ P〈0. 05）. The differences of age,body mass index and triglyceride level between four groups were not statistically significant（ P〉0. 05）. The mortality in elderly male coronary heart disease patients with serum total cholesterol levels 〈4. 16 mmol / L or 〉5. 20 mmol / L increased.Conclusions： The serum total cholesterol level in elderly male patients with coronary heart disease is closely correlated to the mortality.The high or low serum total cholesterol levels are the risk factors of the death of the elderly male patients with coronary heart disease.