中西医结合防治化疗所致消化道延迟反应47例

Forty-Seven Cases of Gastrointestinal Delayed Reaction due to Chemotherapy Treated with Combined Therapy of Traditional Chinese and Western Medicine

目的:观察中西医结合防治恶性肿瘤化疗所致消化道延迟反应的临床疗效。方法:选择94例恶性肿瘤化疗所致消化道延迟反应患者,随机分为对照组和观察组,每组各47例。对照组给予托烷司琼、地塞米松预防消化道反应,观察组在对照组基础上加用降逆止呕中药治疗,观察两组患者的临床疗效、呕吐发生率及生活稳定率。结果:对照组有效率为68.1%,观察组有效率为89.4%,两组有效率比较,差异具有统计学意义(P<0.05)。对照组呕吐发生率为6.4%,观察组呕吐发生率为21.3%,两组比较,差异具有统计学意义(P<0.05)。对照组生活质量改善率为80.9%,观察组生活质量改善率为95.7%,两组比较,差异具有统计学意义(P<0.05)。结论:中西医结合可有效预防恶性肿瘤患者化疗所致的消化道延迟反应,效果显著。

Objective：To observe the clinical curative effect of combined therapy of traditional Chinese and Western medicine on gastrointestinal delayed reaction due to chemotherapy. Methods：Ninety-four patients with malignant tumors due to chemotherapy were randomly divided into the control group and the observation group,with 47 cases in each group. The ones in the control group were given tropisetron,dexamethasone to prevent gastnfintestinal reaction,while the ones in the observation group were added TCM to descend the rising qi and stop vomiting based on the treatment of the control group. Then the two groups＇ clinical curative effects,the vomiting incidence rates and life stability rates were observed. Results： The effective rate of the control group was 68.1% , while that of the observation group was 89.4% ; And the difference between them had statistical significance （ P 〈 0.05 ）. The vomiting incidence rate of the control gnJup was 6.4% , while that of the observation group was 21.3% ;And the difference between them had statistical significance（P 〈 0.05 ）. The life quality improvement rate of the control group was 80.9% , while that of the observation group was 95.7% ; And the difference between them had statistical significance （ P 〈 0.05 ）. Conclusion ： Combined therapy of traditional Chinese and Western medicine has a remarkable clinical curative effect on gastrointestinal delayed reaction due to chemotherapy.