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阿尔茨海默病发病机制研究进展 被引量:11

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摘要 阿尔茨海默病(AD)是一种与年龄相关的中枢神经系统退行性变,临床表现主要为患者记忆力减退、认知功能障碍、语言障碍、丧失生活自理能力等神经行为异常。特征性病理改变为B淀粉样蛋白(Aβ)在脑内沉积形成的老年斑(SP)和tau蛋白高度磷酸化形成的纤维缠结及神经元细胞数目的减少等。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第10期2545-2548,共4页 Chinese Journal of Gerontology
基金 江西省教育厅青年科学基金项目(GJJ11060)
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