下肢静脉曲张与精索静脉曲张的相关性研究

The prevalence of varicocele in male patients with primary varicose vein of the lower extremity

目的探讨下肢静脉曲张与精索静脉曲张之间的相关性。方法选择100例下肢静脉曲张患者作为实验组，100例无血管疾病成人作为对照组，将2组之间精索静脉曲张患病率、临床及超声学指标进行对比。结果实验组与对照组年龄对比差异无统计学意义（t=1．78，P〉0．05）。实验组精索静脉曲张患病率高于对照组（x2=20．05，P〈0．01）。实验组中，存在与不存在股隐瓣膜返流的患者精索静脉曲张患病率差异无统计学意义（r=3．31，P〉0．05），2组间精索静脉直径差异无统计学意义（t=389．00，P〉0．05）。实验组中下肢静脉曲张合并精索静脉曲张的患者中，同一患者的两种静脉的直径大小呈直线相关（等级相关系数rs=0．4072，P〈0．01）。不同CEAP分级的下肢静脉曲张患者精索静脉曲张患病率无明显差异（，=0．8798，P〉0．05），精索静脉平均直径差异也无统计学意义（F=1．59，P〉0．05）。结论下肢静脉曲张和精索静脉曲张的患病存在一定相关性。

Objective To study the correlation between male primary varicose vein of the lower extremity and varicocele. Methods 100 male patients with varicose vein of the lower extremity were compared with 100 male adults without varicose vein of the lower extremity for the prevalence of varicocele by using ultrasonography. Results There is no difference of demographic data between the two groups （ t = 1.78 ,P 〉0. 05）. There were 49 （49. 0% ） patients found with varicoele in study group compared with 19 （ 19. 0% ） patients with varicoele in control group （X2 = 20. 05, P 〈 0. 01 ）. We compared the rate of varicoele and the mean diameter of spermatic vein between the patients having reflux in the saphenofemoral junction or not, and found there was no statistical difference between them （ rate of varicose P 〉 0. 05, diameter P 〉 0.05 ）. In patients with both lower extremity varicose vein and varicocele there was a linear correlation between spermatic vein diameter and that of varicose vein （ r = 0. 407 2, P 〈 0. 01 ）. When patients in study group were classified into six grades by Clinical- Etiology- Anatomy- Pathophysiology （CEAP） trend chi-square found no difference in the incidence of varieoele （X2 =0. 879 8, P 〉0. 05）, nor the mean diameter of spermatic vein in different grades （ F = 1.59, P 〉 0.05 ）. Conclusion There is a correlation between varicose vein of the lower extremity and the pathogenesis of varicocele.