基于聚类和因子分析的糖尿病早期微血管病变证素研究

Researoh on TCM syndrome elements of early diabetic microangiopathy based on cluster and factor analysis

目的:提取糖尿病早期微血管病变的常见中医证素。方法:对通过临床调查获取的531例糖尿病早期微血管病变患者的四诊信息,采用聚类分析和因子分析对获取的症状内部联系进行诠释,提取常用的中医证素。结果:通过聚类分析共获取28个症状组合,因子分析共获取30个公因子。经初步分析,糖尿病早期微血管病变的主要病性证素有气虚、阴虚、阳虚、热、湿、燥、血瘀、气滞、气郁、气逆、血虚等,病位证素有肾、肝、脾、肺、胃等。结论:通过运用聚类和因子分析对基于临床调查的糖尿病早期微血管病变四诊信息进行证素分析,获取的一些症状组合对本病的证候学研究有一定参考价值。

Objective:To research common TCM syndrome elements of early diabetic microangiopathy by cluster and factor analysis.Methods:Totally of 531 of patients with early diabetic microangiopathy were included in this current study, whose four diagnostic parameters were analyzed by cluster and factor analysis to obtain common TCM syndrome elements.Results:The results of cluster analysis showed that there were 28 symptom combinations, and the results of factors analysis showed that there were 30 common factors.These indicated that syndrome elements of disease nature in early diabetic microangiopathy mainly involved qi deficiency, yin deficiency, yang deficiency, heat, dampness, dryness, blood stasis, qi stagnation, qi depression, reversed flow of qi blood deficiency and so on, the syndrome elements of disease location mainly involved the kidney, liver, spleen, lung, stomach, and so on.Conclusion:The results of the study that common TCM syndrome elements in early diabetic microangiopathy obtained by means of cluster and factor analysis have a wider significance for understanding of TCM syndrome of early diabetic microangiopathy.