基于主成分分析和因子分析法的功能性腹胀证候特征研究

Study on the syndrome characteristics of functional abdominal distension based on principal component analysis and factor analysis

目的:基于主成分分析和因子分析的方法探索功能性腹胀病中医证候特征。方法:纳入功能性腹胀患者共300例,用Excel建立临床资料数据库,将患者性别、年龄及中医症状积分等录入并保存,核实无误后导入SPSS统计软件进行主成分分析和因子分析。结果:用主成分分析法提取具有相对独立性且特征值均在1.0以上的11个主成分,累积贡献率为67.944%。通过因子旋转法提取11个因子组合结合中医理论分析得出功能性腹胀证候:实证:肝胃不和(13.541%)、肠道实热(9.922%)、肝脾不和(6.558%)、胃火炽盛(6.108%)、胃肠湿热(5.393%)、肝胃郁热(4.689%)、痰湿中阻(4.251%)、脾胃不和(3.666%);虚证:脾胃虚寒(7.139%);虚实夹杂证:肝郁脾虚(3.484%)、脾虚湿盛(3.194%)。结论:运用主成分分析和因子分析法可更为客观准确的分析功能性腹胀中医证候特征。

Objective: To explore the syndrome characteristics of TCM of functional abdominal distension based on the methods of principal component analysis and factor analysis. Methods: A total of 300 patients with functional abdominal distension were enrolled, using Excel to establish a clinical data database, the patient's gender, age and TCM syndrome scoring were recorded and stored. The SPSS statistical software was used to analyze the principal component analysis and factor analysis. Results: The principal component analysis was used to extract 11 principal components with relative independence and eigenvalues of 1.0 or more, and the cumulative contribution rate was 67.944%. The functional abdominal distension syndrome was obtained by using the factor rotation method to extract 11 factors combined with the analysis of traditional Chinese medicine theory: Excess syndrome: incoordination between liver and stomach(13.541%), intestinal excess heat(9.922%), incoordination between the liver and the spleen(6.558%), exuberance of stomach fire(6.108%), damp-heat in the stomach and intestine(5.393%), syndrome of liver-stomach heat(4.689%), phlegm retention in the middle energizer(4.251%), incoordination between the spleen and the stomach(3.666%); Deficiency syndrome: deficiency cold of spleen and stomach(7.139%); syndrome of intermingled deficiency and excess: stagnation of liver qi and spleen deficiency(3.484%), excessive dampness due to deficiency in spleen(3.194%). Conclusion: Using the methods of principal component analysis and factor analysis, the syndrome characteristics of functional abdominal distention can be analyzed more objectively and accurately.