太冲不同穴位配伍针刺对原发性高血压患者24h动态血压的影响

Effects of acupuncture on Taichong(LR3) with different acupoints compatibility of 24-hour ambulatory blood pressure on patients with essential hypertension

目的:观察不同穴位配伍针刺对原发性高血压患者的降压效应。方法:将163例原发性高血压患者随机分为太冲组、蠡沟组、内关组、非穴组、太冲配蠡沟组、太冲配内关组和太冲配非穴组。针刺隔日1次,每周3次,共治疗4周。在治疗前、疗程结束时以及结束后4周分别测量24h动态血压。结果:治疗12次后,24h平均收缩压均值组间比较,太冲配内关组与太冲配蠡沟组较非穴组、太冲组、内关组、太冲配非穴组下降(P<0.05);各组白天动态平均收缩压与非穴组比较均显著下降(P<0.05);太冲配蠡沟组、太冲配内关组夜间动态平均收缩压与非穴组比较,差异有统计学意义(P<0.05);治疗12次后,24小时平均舒张压均值各组比较差异均无统计学意义;与治疗前比较,太冲组、太冲配蠡沟组、太冲配内关组、太冲配非穴组24h平均收缩压和舒张压均值均显著下降(P<0.05);4周后随访,太冲组、太冲配内关组24h及夜间收缩压和舒张压均值与治疗前比较均显著下降(P<0.05)。结论:针刺降压具有穴位特异性,经穴配伍的降压效应优于单穴与非穴;针刺降压具有一定的远期效应。

Objective: To observe the anti-hypertension effect of different compatibility of acupoints on patients with essential hypertension. Methods: A total of 163 patients with essential hypertension were collected and randomly divided into the Taichong(LR3) group, the Ligou(LR5) group, the Neiguan(PC6) group, the non-acupoint group, the Taichong plus Ligou group(LR3+LR5), the Taichong plus Neiguan group(LR3+PC6) and the Taichong(LR3) plus non-acupoint group. The acupuncture was applied once every other day, 3 times a week for 4 weeks continuelly, 12 times in total. Twenty-four-hour ambulatory blood pressure was examined before and at the end of the treatment, and 4 weeks after the treatment. Results: Compared with non-acupoint group, LR3 group, PC6 group and LR3 plus non-acupoint group, the 24 h dynamic change of systolic blood pressure on LR3+LR5 group and LR3+PC6 group decreased significantly after 12 times treatments(P<0.05). Compared with non-acupoint group, the average systolic blood pressure during the day on all groups decreased significantly(P<0.05), besides, the average systolic blood pressure at night on LR3+LR5 group and LR3+PC6 group also decreased significantly(P<0.05). There was no difference of the change of 24 h dynamic diastolic blood pressure among all groups after 12 times treatments. After the end of treatment, the change of 24 h dynamic systolic blood pressure on LR3 group, LR3+LR5 group, LR3+PC6 group, LR3 plus non-acupoint group declined compared with that before treatment, the difference was statistically significant(P<0.05). Follow-up 4 weeks, the change of dynamic systolic and diastolic blood pressure during the day, night and 24 h on LR3 group and LR3+PC6 group declined compared with that before treatment(P<0.05). Conclusion: Acupuncture has acupoint specificity, and the effect of acupoint compatibility is better than that of single and nonacupoint, acupuncture also has a long term effect on depressurization.