阿尔茨海默病与睡眠障碍的神经发生关联机制研究进展

Research progress on the mechanism of neurogenesis between Alzheimer's disease and sleep disorders

阿尔茨海默病(AD)是一种常见的慢性神经退行性疾病。大量研究表明,睡眠障碍与AD之间存在交互作用。一方面睡眠障碍是AD患者的主要精神症状之一,另一方面睡眠障碍可能是导致或加重AD的危险因素。改善AD患者的睡眠质量已被认为是AD治疗中不可或缺的一部分。因此文章综述AD与睡眠障碍的神经发生关联机制的研究进展,为防治失眠提供科学依据,并为治疗AD开辟新的思路。

Alzheimer's disease(AD) is a sort of common chronic neurodegenerative disease. A large number of studies have shown that sleep disorders and AD have interactions between each other.On the one hand, sleep disorders are one of the main mental symptoms of AD patients. On the other hand, sleep disorders may be a risk factor for causing or exacerbating AD. Improving the sleep quality of AD patients has been regarded as an indispensable part of AD treatment. Therefore,this paper intends to explore the mechanism of neurogenesis between AD and sleep disorders, provide scientific basis for the prevention and treatment of insomnia, and open up new ideas for AD treatment.