中医血瘀证与骨质疏松症关系的研究

Study on the relationship between syndrome of blood stasis and osteoporosis

中医对于骨质疏松症(OP)的认识可以追溯至《黄帝内经》,提出了"骨痿""骨痹""骨枯"等论断。临床上中医治疗OP往往需要从肾论治,兼顾健脾,而活血化瘀之法亦必不可少,活血化瘀治法针对OP骨重建平衡紊乱和骨微观结构退化问题改善其根源,促使新骨化生,旧骨守位。许多专家普遍发现,OP患者存在着舌下脉络曲张、舌紫暗有瘀斑瘀点、皮肤黏膜出现瘀斑、口唇齿龈显现暗红等表现,与中医血瘀证状十分相符。本研究依据《骨质疏松病例中医辨证分型观察表》证状标准,统计就诊于中国中医科学院西苑医院400份OP病例,通过对其骨密度、血瘀证候、舌下络脉血瘀程度、疼痛程度、脉搏波传导速度和骨折次数进行检测或评分。依据实验结果,分析骨密度与以上参数的相关性,进而论证中医血瘀证的存在与OP有着密切的联系。

The knowledge of osteoporosis in traditional Chinese medicine(TCM) can be traced back to Huangdi Neijing, where several concepts such as ‘bone atrophy', ‘bone impediment' and ‘bone necrosis' were put forward. In TCM clinic, osteoporosis treatment often need to focus on treating kidney combined with fortifying the spleen, and activating blood circulation to dissipate blood stasis is also essential. For bone remodeling balance disorders and bone microstructural degeneration, the treatment method of activating blood circulation to dissipate blood stasis can improve its root causes with promoting new bone metaplasia and preventing old bone degeneration. Many experts generally find patients with osteoporosis have the symptoms of sublingual varicose veins, dark purple tongue with ecchymosis or petechiae, ecchymosis in skin mucous membrane, dark red of lips and gingiva, etc, which are very similar to the symptoms of blood stasis in TCM. In this study, a total of 400 cases of patients with osteoporosis in Xiyuan Hospital Affiliated to China Academy of Traditional Chinese Sciences were calculated according to the Observation Table for the Standard of Pattern Classification Based on TCM Identification in Osteoporosis Cases. The bone mineral density, blood stasis pattern, sublingual vascular stasis degree, pain degree, pulse wave velocity and fracture count were tested or scored. According to the experimental results, the correlation between bone mineral density and the above parameters is analyzed, and then the close relationship between TCM blood stasis and osteoporosis is expounded and proved.