中医药治疗儿童过敏性紫癜性肾炎的研究进展

Research progress of traditional Chinese medicine in the treatment of pediatric Henoch-Schonlein purpura nephritis

文章对近年来中医药治疗儿童过敏性紫癜性肾炎的中医研究进展做一综述,从病名、病因病机及辨证论治三大方面进行总结。中医对该病病因病机有独特认识,历代医家观点总结为外感时邪、血热妄行和肺脾肾虚,而现代医家的新认识包括毒邪理论、络病理论、瘀血理论及肝脾失调。中医辨证治疗主要分为早、中、后三期及风热证、血热证、阴虚证及气阴两虚证四型。此外,自拟方及中成药的临床研究显示中医药通过对患者免疫功能、炎性反应及血液高凝状态的改善而起效。

The review summarized the research progress of traditional Chinese medicine in the treatment of pediatric Henoch-Schonlein purpura nephritis in recent years, including disease name, etiology, pathogenesis and differential treatment. Chinese medicine has a unique understanding about the etiologies and pathogenesis of pediatric Henoch-Schonlein purpura nephritis. The syndrome summarized by doctors of past dynasties concludes as exogenous evil, bleeding due to blood-heat and lung, spleen and kidney three organs deficiency. And by modern doctors, syndrome concludes in toxin theory, collateral theory, blood stasis theory and liver-spleen imbalance. Differential treatment sums up to early, medium and later three staging therapies, meanwhile wind-heat syndrome, blood-heat syndrome, yin deficiency syndrome, yin and qi deficiency syndrome four typing therapies. Moreover, clinical study of self-prescription and Chinese patent medicine treatment indicate that Chinese medicine can take effect by the way of improving immune function, inflammatory response and hypercoagulable state.