李达从毒辨治血液肿瘤思路与临证经验

Thought and experience of LI Da in treating hematological tumors from syndrome differentiation and treatment of toxicity

恶性血液肿瘤多数起病急,变化快,病情重。李达教授据三十载血液病临证经验,总结其因毒致病、因病致虚的病机特点,认为白血病因温毒致病,属"血癌"范畴,病位在骨髓,病机为精气亏虚,伏邪内陷,邪正交争所致,变化多端,属于难治之证;淋巴瘤属"恶核"范畴,因痰毒致病,病位在三焦,病机本质为脾虚痰积;骨髓瘤属"髓瘤"范畴,因瘀毒致病,病位在骨髓,与肾相关,肾虚血瘀毒蕴为其病机本质。临证从毒辨治,以毒攻毒、和解排毒、解毒生血,共奏扶正祛邪、固本澄源之效。

Hematologic malignancies are characterized by acute onset, critically illness, and progressing rapidly.Based on the clinical experience of thirty years in treating hematological diseases professor LI Da summarizes the pathogenesis characteristics of the disease caused by toxin causing disease and asthenia due to illness. Leukemia is caused by febrile virulence and is located in bone marrow belongs to ‘blood cancer’. Pathogenesis is due to deficiency of vital energy, sinking of underlying pathogenic factors, orthogonal disputes of pathogenic factors, and various changes, which belong to intractable syndrome. Lymphoma belongs to the category of ‘malignant nucleus’. It is caused by phlegm and toxin. It is located in Sanjiao,and its pathogenesis is essentially spleen deficiency and phlegm accumulation. Myeloma belongs to the category of ‘myeloma’.It is caused by blood stasis and toxin. It is located in bone marrow and related to kidney. Its pathogenesis is essentially kidney deficiency, blood stasis and toxin accumulation. Clinical treatment from toxin evil, fight poison, reconciliation detoxification,detoxication and engendering blood, played the total effect of strengthening the body resistance and eliminate pathogenic factors.